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| [2008] 11. Ki Min Seong, Seong Yeon Yoo, Jung Ho Hwang, Nam Soo Cho, Seong Ho Kim, Young Shik Choi |
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| Poster :
Date : 09-11-09 21:58
Hit : 1467
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Publication; issue : 2008 Year 32 Vol 1 iss 68 p
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  (235.1K), Down : 70, 2009-11-09 21:58:02 | |
Change of surname? : An application of Y-STR haplotyping
Kor J Legal Med 2008 May;32(1):68-71.
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Department of Forensic Medicine, Central District Office, NISI, Daejeon 305-348, Korea. cns6999@nisi.go.kr
Y-STR haplotyping is a powerful forensic and anthropological tool for identifying male lineages. We used high-resolution Y-STR haplotyping to evaluate the possibility of an ancestral relationship between two individuals with the different surname. Of the 17 Y-STRs genotyped, 16 had identical alleles in two individuals, except for an unambiguously sporadic mutation (one-step mutation) at DYS385 locus. The common allele 11.1 (U3Ains) at DYS439 locus was also observed in these two individuals. Sequencing analysis of these alleles of two samples demonstrated an A insertion at base 3 upstream from the repeat region's first GATA motif. These findings suggested that two individuals were paternally related, even if male individuals live with different surname.
Key words : Y-STR, surname, haplotypes, mutation
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