HOME사이트맵Eng
학회소개 학회일정 학회지 토론방 게시판 자료실 관련사이트


  학회지  
     학회지 소개 
     편집위원 
     논문투고규정 
     학회지 검색 


학회지 검색
    > 학회지 검색 >>  2020
  [2020] 3. Jong-Pil Park, Bon Young Koo, Nak-Won Lee
  Poster :      Date : 20-06-04 13:38     Hit : 830    
  Publication; issue :  2020 Year  44 Vol  2 iss  76 p
   (4.8M), Down : 90, 2020-06-04 13:38:44

Postmortem Diagnosis of Anaphylactic Shock by Histopathological Examination of Mast Cell

Korean J Leg Med 2020;44:76-83

Department of Forensic Medicine, Yonsei University College of Medicine, Seoul, Korea,

Division of Forensic Medicine, National Forensic Service Daegu Institute, Chilgok, Korea,

Division of Forensic Medicine, National Forensic Service Daejeon Institute, Daejeon, Korea

E-mail: parkjp@yuhs.ac

An autopsy for a fatal anaphylactic shock (AS) is not rare; however, postmortem diagnosis of anaphylaxis can be very challenging due to nonspecific macroscopic findings and absence of diagnostic tests except serum mast cell tryptase analysis. We tried to review the usefulness of histopathologic examination as an alternative method for the postmortem diagnosis of AS in this study. Immunohistochemical staining was carried out for detection of mast cells in 27 autopsy cases, including 7 AS cases, 5 false-positive cases, and 15 control cases at the National Forensic Service from January 2013 to May 2015, and the differences of mast cell counts and staining pattern were analyzed. The results revealed no differences in the number of mast cells among the three groups; however, a characteristic mast cell degranulation staining pattern was observed in the AS group and false-positive group. It can be conclusively inferred that the histopathologic examination could prove helpful in the postmortem diagnosis of AS, but it should serve as an ancillary option.

Key Words: Anaphylaxis; Mast cells; Autopsy; Pathology



   hit   datetime
Total 613
Category  iss Date / Subject / Contents / Writer
2020 (3) 6. Moonhee Jung, Su Jin Lee, Seong Ho Yoo2, Hyung-Seok Kim

Death from 2,4-Dinitrophenol Poisoning: An Autopsy Case

Korean J Leg Med 2020;44:140-142

2020 (3) 5. Milim Kim, Soong Deok Lee, Moon-Young Kim

Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning

Korean J Leg Med 2020;44:134-139

2020 (3) 4. Young-Hoon Jo, Bo-Kyung Kong, Ji-Sook Min, Inseok Choi, J…

Two Cases of the Postmortem Testing of Ethyl Glucuronide and Beta-hydroxybutyrate for Chronic Alcoholism

Korean J Leg Med 2020;44:129-133

2020 (3) 3. Yun Seol Na, Ji Hye Park

Unusual Asphyxia: Two Autopsy Cases Report

Korean J Leg Med 2020;44:123-128

2020 (3) 2. Gi Yeong Huh

Progress in Method and Reliability of Diatom Test in Drowning

Korean J Leg Med 2020;44:115-122

2020 (3) 1. Youn Shin Kim, Tae Eun Kim

Proposal of Comprehensive Act for Postmortem Examination to Improve Death Certification System

Korean J Leg Med 2020;44:103-114

2020 (2) 6. Min Jee Park, Ock Kim, Hongil Ha

Death by Nitrite Intoxication: Report of 14 Cases

Korean J Leg Med 2020;44:96-101

2020 (2) 5. Yonghan Jung, Sangbum Lim, Youngsan Ko, Seonjung Jang, Hy…

Fatal Complications of Dental Implant Surgery: An Autopsy Case Report

Korean J Leg Med 2020;44:92-95

2020 (2) 4. Ji Eun Park, Su Jin Jeong, Sang Hyun Park, Sang Eon Shin,…

A Comparison of Growth Curve Models for Forensically Important Flies Using Sigmoid Functions

Korean J Leg Med 2020;44:84-91

2020 (2) 3. Jong-Pil Park, Bon Young Koo, Nak-Won Lee

Postmortem Diagnosis of Anaphylactic Shock by Histopathological Examination of Mast Cell

Korean J Leg Med 2020;44:76-83

 1  2  3  4  5  6  7  8  9  10    

24시간 동안 이 창을 다시 열지 않음
24시간 동안 이 창을 다시 열지 않음
24시간 동안 이 창을 다시 열지 않음