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    > 학회지 검색 >>  2020
  [2020] 5. Milim Kim, Soong Deok Lee, Moon-Young Kim
  Poster :      Date : 20-09-03 13:54     Hit : 811    
  Publication; issue :  2020 Year  44 Vol  3 iss  134 p
   (1.4M), Down : 168, 2020-09-03 13:54:49

Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning

Korean J Leg Med 2020;44:134-139

Department of Pathology, Seoul National University Bundang Hospital, Seongnam, Korea,

Department of Pathology, Seoul National University College of Medicine, Seoul, Korea,

Department of Forensic Medicine, Seoul National University College of Medicine, Seoul, Korea,

Institute of Forensic and Anthropological Science, Seoul National University College of Medicine, Seoul, Korea

E-mail: tttrack@naver.com

Acetaminophen or paracetamol (N-acetyl-para-aminophenol [APAP]) is a safe and effective antipyretic and analgesic drug and is a representative nonprescription drug. However, APAP is one of the most common nonprescription drugs used for intentional overdose or suicide, thereby resulting in hundreds of deaths annually in the United States. Moreover, the misuse of nonprescription drugs is a cause of increasing concern in Korea with the revision of the Pharmaceutical Affairs Law in 2012. Generally, the mortality rate of APAP overdose is extremely low due to the well-established treatment guidelines and availability of antidotes. However, it should not be overlooked because of the high number of either accidental or intentional APAP overdose cases recorded every day. To achieve a good prognosis, individuals with APAP overdose must be immediately identified and brought to the hospital. Herein, we report an autopsy case of an individual with APAP overdose who died due to acute liver injury.

Key Words: Nonprescription drugs; Acetaminophen; Drug-induced acute liver injury; Suicide; KIDS KAERS database (KIDS-KD)



   hit   datetime
Total 613
Category  iss Date / Subject / Contents / Writer
2020 (3) 6. Moonhee Jung, Su Jin Lee, Seong Ho Yoo2, Hyung-Seok Kim

Death from 2,4-Dinitrophenol Poisoning: An Autopsy Case

Korean J Leg Med 2020;44:140-142

2020 (3) 5. Milim Kim, Soong Deok Lee, Moon-Young Kim

Intentional Death Caused by the Overdose of Nonprescription Drugs: An Autopsy Case of Acetaminophen Poisoning

Korean J Leg Med 2020;44:134-139

2020 (3) 4. Young-Hoon Jo, Bo-Kyung Kong, Ji-Sook Min, Inseok Choi, J…

Two Cases of the Postmortem Testing of Ethyl Glucuronide and Beta-hydroxybutyrate for Chronic Alcoholism

Korean J Leg Med 2020;44:129-133

2020 (3) 3. Yun Seol Na, Ji Hye Park

Unusual Asphyxia: Two Autopsy Cases Report

Korean J Leg Med 2020;44:123-128

2020 (3) 2. Gi Yeong Huh

Progress in Method and Reliability of Diatom Test in Drowning

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2020 (3) 1. Youn Shin Kim, Tae Eun Kim

Proposal of Comprehensive Act for Postmortem Examination to Improve Death Certification System

Korean J Leg Med 2020;44:103-114

2020 (2) 6. Min Jee Park, Ock Kim, Hongil Ha

Death by Nitrite Intoxication: Report of 14 Cases

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2020 (2) 5. Yonghan Jung, Sangbum Lim, Youngsan Ko, Seonjung Jang, Hy…

Fatal Complications of Dental Implant Surgery: An Autopsy Case Report

Korean J Leg Med 2020;44:92-95

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A Comparison of Growth Curve Models for Forensically Important Flies Using Sigmoid Functions

Korean J Leg Med 2020;44:84-91

2020 (2) 3. Jong-Pil Park, Bon Young Koo, Nak-Won Lee

Postmortem Diagnosis of Anaphylactic Shock by Histopathological Examination of Mast Cell

Korean J Leg Med 2020;44:76-83

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