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| [2019] 1. Jong-Pil Park, Tak Su Lee, Minsung Choi, Kyung-moo Yang, Jeongwoo Park, Yujin Won, Jongseok Lee, Duk Hoon Kim, Seung Gyu Choi, Kyunghong Lee, Jeong Hwan Kim, Moa Kim, Miyoung Yu |
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| Poster :
Date : 19-09-04 15:29
Hit : 511
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Publication; issue : 2019 Year 43 Vol 3 iss 91 p
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  (242.1K), Down : 58, 2019-09-04 15:29:24 | |
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Evaluation of the Usefulness of Cardiac
Enzyme Analysis for the Diagnosis of Acute Myocardial Infarction in Postmortem
Inspection
Korean J Leg Med 2019;43:91-96
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Department of Forensic Medicine, Yonsei
University College of Medicine, Seoul, Korea
Division of Forensic Medicine
Investigation, National Forensic Service Seoul Institute, Seoul, Korea
Medical Examiner’s Office, National Forensic
Service, Wonju, Korea
Gyeonggi Nambu Provincial Police Agency,
Suwon, Korea
E-mail: parkjp@yuhs.ac
Acute myocardial infarction is one of the
most common causes of unexpected deaths, but there are limitations to its
diagnosis in postmortem inspection. In this study, we aimed to investigate the
usefulness of cardiac marker analysis for the diagnosis of acute myocardial
infarction in postmortem inspection. This study was conducted on 30 postmortem
inspection cases conducted by the National Forensic Service from 2016 to 2018.
Tests for three myocardial enzymes (myoglobin, creatinine kinase-MB, and
cardiac troponin I) were performed in each case, and the relationships between
enzyme levels, cause of death, and factors affecting the postmortem tests were
analyzed. Cardiac enzyme concentrations were not significantly different
between the heart disease group and other disease groups, and the
false-positive rate was increased due to postmortem changes. Therefore, we can
conclude that it is not appropriate to use cardiac enzyme analysis for the
diagnosis of acute myocardial infarction in postmortem inspection.
Key Words: Myocardial infarction; Diagnosis;
Postmortem changes; Troponin I
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학회지 
