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  [2010] 12. Nam Soo Cho, Seong Yeon Yoo, Jung Ho Hwang, Ki Min Seong, Nak-Eun Chung, Won Tae Lee
  Poster :      Date : 10-12-01 19:17     Hit : 1545    
  Publication; issue :  2010 Year  34 Vol  2 iss  147 p
   (490.9K), Down : 135, 2010-12-01 19:17:24

Null and Duplicated Alleles of 17 Y-STR Haplotypes in Koreans and Considerations for Forensic Application

Korean J Leg Med. 2010 Nov;34(2):147-51. English.

 

Department of Forensic Medicine, Central District Office, National Institute of Scientific Investigation, Daejeon, Korea

Department of forensic Medicine, Eulji University, Daejeon, Korea, wtlee@eulji.ac.kr

 

The analysis of Y chromosome polymorphisms has become common place for the identification of male component in forensic cases. In male/female mixtures of many rape cases, Y-STRs are also very useful for the determination of contributors number. During the analyses of 17 Y-STR haplotypes for forensic applications using the AmpFlSTR® YfilerTM system, a number of null and duplicated alleles (40 out of 2144 subjects) were discovered. Interestingly, two haplotypes should focus the attention on forensic interpretation of Y-STR haplotype profiles, because multiple mutational events at various loci can be interpreted as a wrong mixed or allele drop-out profile.

 

Key words : Y chromosome STR, AmpFlSTR® YfilerTM system, null allele, duplicated allele, database

Original article



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