 |
 |
|
|
|
|
|
[2008] 9. Kyoung-Jin Shin, Hwan Young Lee, Woo Ick Yang, Eunho Ha |
 |
|
|
Poster :
Date : 09-11-09 21:56
Hit : 1454
|
|
Publication; issue : 2008 Year 32 Vol 1 iss 55 p
|
(736.1K), Down : 70, 2009-11-09 21:56:04 | |
Statistical Interpretation in Making DNA-based Identifications of Mass Victims Kor J Legal Med 2008 May;32(1):55-60.
|
|
Department of Forensic Medicine, Yonsei University College of Medicine, Seoul, Korea.
Department of Information and Statistics, Yonsei University at Wonju-si, Gangwon-do, Korea. statha@yonsei.ac.kr
DNA profiles have been increasingly used as the most reliable means to identify remains from war or mass disaster. To establish the identity with such a large set of victims, special care should be taken to correlate remains with correct family references while avoiding coincidental match between non-relatives. Therefore we address here relevant statistical and combinatorial issues in the DNA identification of mass victims. A simple and general formula for the likelihood ratio governing any potential kinship between two DNA profiles was presented, and for that purpose, the probabilities that a given relative and an individual share autosomal identical-bydescent alleles were calculated. In addition, a method dealing with the allele drop-out in kinship analysis and the estimation of a cold hit were discussed.
Key words : mass victims, kinship, relatives, probability, likelihood, allele drop-out, cold hit
|
|
|
|
|
|
|