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| [2010] 12. Nam Soo Cho, Seong Yeon Yoo, Jung Ho Hwang, Ki Min Seong, Nak-Eun Chung, Won Tae Lee |
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| Poster :
Date : 10-12-01 19:17
Hit : 1718
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Publication; issue : 2010 Year 34 Vol 2 iss 147 p
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  (490.9K), Down : 135, 2010-12-01 19:17:24 | |
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Null and Duplicated Alleles of 17 Y-STR Haplotypes in Koreans and Considerations for Forensic Application
Korean J Leg Med. 2010 Nov;34(2):147-51. English.
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Department of Forensic Medicine, Central District Office, National Institute of Scientific Investigation, Daejeon, Korea
Department of forensic Medicine, Eulji University, Daejeon, Korea, wtlee@eulji.ac.kr
The analysis of Y chromosome polymorphisms has become common place for the identification of male component in forensic cases. In male/female mixtures of many rape cases, Y-STRs are also very useful for the determination of contributors’ number. During the analyses of 17 Y-STR haplotypes for forensic applications using the AmpFlSTR® YfilerTM system, a number of null and duplicated alleles (40 out of 2144 subjects) were discovered. Interestingly, two haplotypes should focus the attention on forensic interpretation of Y-STR haplotype profiles, because multiple mutational events at various loci can be interpreted as a wrong mixed or allele drop-out profile.
Key words : Y chromosome STR, AmpFlSTR® YfilerTM system, null allele, duplicated allele, database
Original article
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