 |
 |
|
|
|
|
|
| [2007] 5. Myung Jin Park, Hwan Young Lee, Na Young Kim, Jeong Eun Sim, Woo Ick Yang, Sang-Ho Cho, Kyoung-Jin Shin |
 |
|
|
| Poster :
Date : 09-11-09 21:36
Hit : 1989
|
|
|
Publication; issue : 2007 Year 31 Vol 2 iss 162 p
|
  (249.4K), Down : 137, 2009-11-09 21:36:31 | |
Genetic characteristics of 22 Y-STR loci in Koreans
Kor J Legal Med 2007 Nov;31(2):162-70.
|
|
|
Department of Forensic Medicine, Yonsei University College of Medicine, Seoul, Korea. kjshin@yuhs.ac
Human Identification Research Center, Yonsei University, Seoul, Korea.
To construct a Korean Y-chromosomal STR database for 22 Y-STRs (DYS19, DYS385, DYS388, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438, DYS439, DYS446, DYS447, DYS448, DYS449, DYS456, DYS458, DYS464, DYS635, and GATA H4.1), 708 DNA samples from unrelated Korean males were analyzed using three multiplex PCR systems. During analysis, thirty two microvariant alleles were observed at DYS449, DYS458, and DYS464, and duplicated alleles were occurred once each for DYS19, DYS390, and DYS447. In haplotype analysis for the 22 Y-STRs, a total of 693 different haplotypes were observed with overall haplotype diversity of 0.9999, and of these, 680 haplotypes were unique. By combining each marker for the extended SWGDAM haplotype, DYS458 was the most informative marker. In addition, the diversity of combined haplotypes of DYS447, DYS458, DYS635, GATA H4.1, and the SWGDAM Y-STR loci was comparable to haplotypes of 17 loci in the AmpFlSTR(R) Yfiler(TM) kit.
Key words : Y chromosome, STR, extended SWGDAM haplotype, AmpFlSTRⓇ Yfiler™, microvariant allele, duplicated allele, Koreans
|
|
|
|
|
|
|
|
학회지 
